Mbale is a city in the Eastern Region of Uganda. It is the main municipal, administrative, and commercial center of Mbale District and the surro…Mbale is a city in the Eastern Region of Uganda. It is the main municipal, administrative, and commercial center of Mbale District and the surrounding sub-region. Mbale is approximately 225 kilometres northeast of Kampala, Uganda's capital city, on an all-weather tarmac highway. The city lies at an average elevation of 1,156 metres above sea level.