“The antidepressant effect of aerobic exercise has been convincingly demonstrated through randomized controlled trials, but its mechanism is not well understood,” said Dr Emily Hird from the Institute ...

Depression is not only a disorder of mood but also a condition that affects the heart and blood vessels, and can carry ...

Depression continues to grapple a large proportion of the population. Given the side effects associated with the long-term use of conventional antidepressants, there is a need for novel rapid acting ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, No. 23 (June 10, 2014), pp. 8649-8654 (6 pages) Ketamine is an NMDA receptor (NMDAR) antagonist that elicits ...

The processes in the brain and body through which physical exercise reduces depressive symptoms have been explored by UCL researchers. Depression is the leading cause of disability worldwide and is ...

Activation of the body’s opioid system may be required for ketamine’s antidepressant effects, new research hinted. In a small study of adults with major depressive disorder, taking the opioid blocker ...

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, ...

This is the fifth in a series of posts on non-pharmacologic treatments of depressed mood. Previous posts briefly reviewed research findings on S-adenosylmethionine (SAMe) and folate. This post is ...