In the fight against disease, programmed cell death – also known as apoptosis – is a key protective function of the body. It breaks down cells that are damaged or have undergone dangerous changes.

Cells operate on rules not vibes, including when on the precipice of persisting or perishing. Yet, with prior research ...

Apoptosis Signal-Regulating Kinase 1 (ASK1) is a pivotal member of the mitogen-activated protein kinase kinase kinase (MAP3K) family. It orchestrates cellular responses to a range of stressors—such as ...

In a new study, researchers have identified a way to stop cells from dying, opening the door to developing treatments that slow the progression of neurodegenerative conditions like Parkinson’s disease ...

The activation and deactivation of apoptosis is a promising field of research in basic biomedical research. The team led by Prof. Franz Hagn from the Chair of Structural Membrane Biochemistry at the ...

A breakthrough discovery by scientists at India's CSIR-Centre for Cellular and Molecular Biology (CCMB) has revealed that human cells possess an intrinsic ability to revive from near-death states.

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

In an extensive review, researchers explore ZBP1-mediated programmed cell death and its potential as a therapeutic target for systemic diseases Programmed cell death, or PCD, is an actively regulated ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in ACS Nano, how proteins in cells can be controllably activated through heating, an effect that can be used ...

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed. Aging cells secrete substances known to ...