Discover how robust screening assays enhance data quality and reliability in high-throughput screening for drug discovery.
High-throughput screening (HTS) enables rapid discovery but introduces assay, automation, and data challenges. This article ...
Therapeutic antibodies are now the major class of successful protein drugs with many more in development to target a variety of major diseases. An important and desirable biological activity of most ...
In the ever-evolving landscape of biomedical research, the need for reliable, consistent, and ready-to-use cell models has never been more critical. ATCC, a leading provider of biological materials, ...
Poly(ADP-ribose) polymerase inhibitors (PARPi) have shown promising clinical results in the treatment of ovarian cancer. Analysis of biomarker subgroups consistently revealed higher benefits for ...
You don't want to miss this! To permanently access this eBook for free, fill out the short form below. Developing robust, reproducible antibody pair-based immunoassays is critical for guiding drug ...
A good bioassay, like a good marriage, joins two partners in a bond and is mutually beneficial. In the case of bioassays, optimal design and development and accurate statistical analysis comprise a ...
Friends of Cancer Research initiated a research partnership, inviting HRD assay developers to participate in two blinded analyses. In the first, 11 assay developers reported HRD status for the Cancer ...
Potency assays are essential for product quality and patient safety. These tests enable a direct measurement of a biologic's functional activity, verifying that the therapy works as intended. Potency ...
This poster was originally authored by John Vincent, Matthew Burnham, Gerrit Daubner, and Martin Main of the Medicines Discovery Catapult. It was presented at ELRIG Drug Discovery 2023. Methods to ...