In bile acid diarrhoea, a form of chronic diarrhoea, the body does not recycle bile acids properly. It is most commonly caused when bile acids are overproduced in people who have no damage to the bile ...

You may experience bile acid malabsorption on its own or due to an underlying condition. Doctors typically treat it with medication and by suggesting dietary changes. Bile acid malabsorption (BAM) is ...

Hepatocellular carcinoma is among the leading causes of tumor-related death, and the liver is among the most common sites of cancer metastasis. Several types of immune cells surveil the liver to ...

Could bile acids--the fat-dissolving juices churned out by the liver and gallbladder--also play a role in immunity and inflammation? The answer appears to be yes, according to two separate Harvard ...

There are trillions of microbes in the gastrointestinal tract, and we are starting to learn more about the exact mechanisms that link those microbes and the substances they generate to changes in ...

Researchers suspected these gut microbial modifications could affect how bile acids function and interact with human signaling pathways. To test this idea, the investigators set out to explore the ...

For the first time, a team of experts from the Technical University of Munich (TUM), RWTH Aachen University, and the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) has demonstrated the ...

Probiotic Lactobacillus bacteria use enzymes situationally to manipulate bile acids and promote their own survival in the gut. New research from North Carolina State University reveals that probiotic ...

Researchers headed by teams at the Salk Institute and at the University of California, San Diego (UCSD), have discovered, in mice, how high-fat diets (HFDs) can change gut bacteria and alter digestive ...

Salk scientists discover that removing bile acid-creating protein BAAT and adding bile acid UDCA controls tumor growth in mice with liver cancer; UDCA dietary supplements may be quick solution to ...

The intestine-selective FXR knockout mice were generated by cross-breeding of mice with loxP sites flanking the last FXR exon, containing the ligand-binding domain (described by Sinal et al 4), with ...