New research co-led by Indiana University School of Medicine scientists presents a significant step toward more precise and effective cancer treatments by using a breakthrough method to deliver ...

Breast cancer–derived CTCs exhibit phenotypic plasticity, including epithelial-mesenchymal transition, subtype switching and cluster formation, which is associated with bone metastatic potential. 2.

Researchers at Baylor College of Medicine and collaborating institutions have developed a method that reveals the cellular makeup of tissues that support metastatic cancer growth, which is the primary ...

Bone metastsis in advanced breast cancer patients are usually osteolytic. A better understanding of the mechanisms in osteolytic metastasis is critical for the development of new therapies. YTH domain ...

Cancer specialists have long known that anemia, caused by a lack of healthy red blood cells, often arises when cancer metastasizes to the bone, but it's been unclear why. Now, a research team led by ...

Their key finding was the mechanism by which a normal cell type, mesenchymal stem cells, in the bone marrow supports the cancer cells. "We discovered that the breast cancer cells require direct ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

A bone marrow transplant process co-developed by investigators at the Johns Hopkins Kimmel Cancer Center is safe and curative for adults with sickle cell disease, according to results of a trial ...

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Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...

A 13-year-old baseball player returned to the mound Friday night at Bayshore Little League in Tampa after beating bone marrow ...

Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...