New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...
New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...
Zalicus Initiates the First of Two Phase 2a Studies with Z160, a First-in-Class, Oral, State-Dependent, Selective N-type Calcium Channel Blocker, for the Treatment of Chronic Neuropathic Pain (NASDAQ: ...
Calcium channel blocker (CCB) overdose presents as profound hypotension, bradycardia and, in severe cases, cardiogenic shock. The principal mechanism involves impaired calcium influx into cardiac and ...
When you have atrial fibrillation, the two upper chambers of your heart (atria) don't beat in sync with the two lower chambers (ventricles). This makes your heart beat out of rhythm and sometimes very ...
Two years after Idorsia and Neurocrine’s calcium channel blocker flunked a pair of phase 2 studies in quick succession, the biotechs have finally decided to part ways. Idorsia had initially taken the ...
Active ingredient: Clevidipine butyrate emulsion 0.5 mg/mL; solution for IV infusion; contains lipids 0.2 g/mL (soybean oil, egg phospholipids). Indication: To reduce BP when oral therapy is not ...