Cancer arises when the normal controls on cell growth, differentiation and death are subverted. Under physiological conditions, cells proliferate only in response to external stimuli, replicate their ...

A new wave of scientific understanding is placing ferroptosis, a distinct form of iron-dependent cell death, at the forefront of efforts to overcome drug resistance in digestive cancers. These cancers ...

A newly published review article highlights the critical role of fatty acid metabolism in shaping the tumor microenvironment and influencing cancer progression, offering fresh perspectives for the ...

Understanding and controlling how cancer cells transition between different states remains a critical challenge in tumor ...

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...

University of Cincinnati structural biologists are the first in the world to visualize a key cell protein as part of newly ...

Scientists have uncovered a surprising dark side to vitamin B2: it may help cancer cells stay alive. The vitamin supports a ...

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have ...

Researchers found a new way to kill harmful “zombie” cells that linger after chemotherapy and help cancers become more ...

Chemotherapy drugs like doxorubicin and etoposide work by snapping a cancer cell’s DNA in two. The breaks are supposed to be ...

Scientists at UCLA have developed an "off-the-shelf" cell-based immunotherapy that was able to track down and kill pancreatic cancer cells even after they had spread to other organs. In a mouse study, ...