Worldwide, more than a million breast cancer patients have been treated with cyclin-dependent kinase 4/6 (CDK4/6) inhibitors, ...

A new review in Nature Reviews Drug Discovery highlights the potential for CDK4/6 inhibitors, currently approved for certain breast cancers, to treat a wider range of cancers. Researchers from Roswell ...

Chimeric antigen receptor (CAR) T-cell therapy is one of oncology's most powerful ideas: Harvest a cancer patient's own immune cells, genetically engineer them to recognize tumor cells, multiply them ...

Chronic myeloid leukemia may seem to appear suddenly, but new research shows it begins years before diagnosis with an explosive surge of growth. Scientists tracked how a single genetic accident—the ...

A new study suggests the mechanical force of heartbeats can suppress cancer cell growth, potentially explaining why heart cancer is extremely rare. Researchers identified the protein Nesprin-2 as a ...

An important element in getting blood stem cells to multiply outside the body is to understand which of the approximately 20,000 genes in the human body control their growth. Now a research team at ...

For years, one of the most powerful weapons against certain blood cancers, called CAR-T therapy, has required an elaborate process: Doctors extract a patient’s immune cells, ship them to a specialized ...