Immune checkpoint blockade (ICB) has reshaped the treatment landscape for advanced hepatocellular carcinoma (HCC), offering ...

A panelist discusses how tumor heterogeneity (both spatial and temporal) affects molecular testing reliability in ovarian cancer, highlighting that although most biomarkers show little heterogeneity, ...

Digestive system cancers, including hepatobiliary and gastrointestinal malignancies, remain a major global oncological burden ...

Recent advances in single-cell sequencing and spatial multi-omics have transformed our ability to resolve tumor ecosystems at unprecedented resolution.

Visualization in the UMAP space of samples corresponding to the subtypes ER+ (a), HER2+ (b), and TN (c). The samples were categorized by cancer subtype and integrated. Cells are color-coded according ...

The researchers have developed a novel deep learning framework that integrates high-resolution pathology images with spatial transcriptomics and proteomics to reveal the complex intra-tumor ...

Extrachromosomal DNAs (ecDNAs) are circular DNA structures located in the nuclei of cells outside chromosomes. They were originally discovered in chromosome spreads of cells obtained from embryonal ...

Researchers report encouraging early results from a first-in-human clinical trial led by Children's National Hospital using a ...

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new platform that combines 3D bioprinting ...

Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most ...