T cell activation is governed by a dual-signal paradigm in which the antigen-specific engagement of the T-cell receptor (TCR) (Signal 1) must be complemented by costimulatory signals (Signal 2) to ...
Understanding how immune cells coordinate within the tumor microenvironment is essential for developing effective cancer immunotherapies. While CD8⁺ cytotoxic T cells are central to anti-tumor ...
Cancer immunotherapy has represented a significant advancement in cancer treatment; however, many patients experience relapse or develop resistance to this treatment. Bispecific antibodies that ...
Sjögren’s disease (SjD) is a chronic, multisystem autoimmune disorder characterised by lymphocytic infiltration of exocrine ...
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