Figure 1: Structural consequences of the conversion from Abi to D4A that occurs both in mice and in patients, and requires 3βHSD. Figure 2: D4A inhibits 3βHSD, CYP17A1 and 5α-reductase enzymatic ...

Metastatic prostate cancer generally responds initially to medical or surgical castration but eventually develops into castration-resistant prostate cancer (CRPC), which is driven by the metabolic ...

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Evaluating abiraterone responses in African Americans with metastatic CRPC. This is an ASCO Meeting Abstract from the 2016 Genitourinary Cancers Symposium. This abstract does not include a full text ...