DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

Bacteria that are resistant to antibiotics thrive in the face of drug treatment, which can lead to life threatening, often incurable infections. Other bacteria can exist in a pre-resistant state. To ...

The circadian rhythm is the body's clock, and it influences physiology at the cellular level; it can help animals, including humans, know when it's time to eat, wake up or go to sleep. Recent work has ...

Scientists have uncovered how DnaA, the master key to DNA replication, opens the door to bacterial growth. This breakthroughpaves the way for new antibiotics to combat the rising tide of antibiotic ...

A new study has revealed that certain locations of DNA are copied faster than others, which could also have an effect on mutation rate. Cell division is fundamental for life, allowing organisms to ...

Scientists have discovered that bacteria can reshape their DNA to survive dehydration. The research, published today in the journal Proceedings of the Royal Society Interface, shows that bacterial DNA ...

Here we show that DNA polymerases derived from the bacterium E. coli are considerably more prone to errors under microgravity, such as occurs in space. Our results thus have important implications for ...

Bacterial DNA methylation occurs at diverse sequence contexts and plays important functional roles in cellular defense and gene regulation. An increasing number of studies have reported that bacterial ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...