The Broad Cancer Dependency Map team adds CRISPR-based data from 342 cancer cell lines to their growing catalog of genetic dependencies in cancer, and a new method for ensuring that data's accuracy.

"Dependency" mapping reveals the genetic adaptations cancer cells make to survive. And while this approach is helping identify promising treatment strategies for several cancer types, researchers have ...

Cancer dependency maps have accelerated the discovery of essential genes and potential drug targets. Here we used machine learning to build translational dependency maps of patients’ tumors and normal ...

Researchers on the Broad Institute's Cancer Dependency Map (DepMap) team have released DEMETER2, an upgraded version of an open source software tool that identifies cancer cells' genetic dependencies ...

Cancer cells are infuriatingly good at surviving when they shouldn’t. The nimble cells are able to adapt to a slew of mutations and molecular errors, persisting and spreading within the body as a ...

In one of the largest efforts to build a comprehensive catalog of genetic vulnerabilities in cancer, researchers have identified more than 760 genes upon which cancer cells from multiple types are ...

April 15, 2026 (Cambridge, MA) — The Broad Institute’s Cancer Dependency Map Consortium (DMC) is an academic-industry collaboration that has transformed the study of cancer by developing one of the ...