Chinese researchers develop world's first large-scale 2D metal material, unlocking future tech revolution
A Chinese research team has successfully developed a single-atom-thick metal layer, with a thickness just one ...
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Detecting problems during protein synthesis with a firefly luciferase-based reporter
A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER), as reported by researchers at Science Tokyo.
Nature14d
Cell death discovery adds fresh angle to attack cancer
Cystine contains reactive disulfide bonds that can react with various proteins throughout the cell, with toxic effect. Cells use the reducing agent NADPH to neutralize cystine, and NAPDH is mainly ...
News Medical1mon
Targeted polymersomes boost methotrexate efficacy for aggressive choriocarcinoma treatment
The high concentration of glutathione within choriocarcinoma cells reacts with the internal disulfide bonds of the polymersome to breakdown the nanocarrier and release methotrexate into the cell.