Enzymes are proteins that can change shape and therefore become active or inactive. An activator molecule (green pentagon) can bind to an enzyme (light green puzzle shape) and change its overall shape ...

CHANGES of volume accompanying enzyme hydrolysis have been utilised by Sreenivasaya and Sastry 1 to follow the kinetics of enzyme action by means of the dilatometer. The procedure employed in the ...

Enzyme kinetics involves the measurement of the rate at which chemical reactions that are catalyzed by enzymes occur. Knowledge about the kinetics of an enzyme can reveal useful information about its ...

Cravatt’s strategy for ferreting out new inhibitors for multiple enzymes simultaneously is a good example “of how a strong understanding of enzyme mechanisms can serve as a starting point for studies ...

Researchers defined the structure of a substrate-bound iron 2-oxoglutarate (Fe/2OG) enzyme to explore whether these enzymes could be used to create a wide array of molecules. They saw that Fe/2OG ...

Real-time measurement of the initial stage of an enzyme–substrate reaction is essential for reproducible enzyme kinetics data. Automated direct-flow injection systems couple with various detection and ...

A clever means of localizing and confining enzymes and the substrate molecules they bind with has been presented by researchers, speeding up reactions essential for life processes. Living systems rely ...

Chemists at MIT have introduced an engineered biosynthetic enzyme that accepts a wider range of substrates into periwinkle plant culture to make unnatural analogs of alkaloids (Nat. Chem. Biol., DOI: ...

A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was identified by researchers at the Institute of Science Tokyo.

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...

An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance. Key details in the enzyme-driven biosynthesis of a natural molecule with ...