This is a preview. Log in through your library . Abstract Amyloid-β (Aβ) fibrils exhibit self-propagating, molecular-level polymorphisms that may contribute to variations in clinical and pathological ...

A new imaging technique developed by engineers at Washington University in St. Louis can give scientists a much closer look at fibril assemblies, stacks of peptides like amyloid beta, most notably ...

For some years now scientists have been trying to elucidate the physics behind amyloid fibrils, the multimeric and insoluble strands that cause a variety of amyloidoses, including the plaques of ...

Amyloid fibrils are deposits of proteins in the body that join together to form microscopic fibres. Their formation has been linked to many serious human diseases including Alzheimer's, Parkinson's ...

Two papers in PNAS add to the growing body of work aimed at understanding the molecular interactions involved in the formation of amyloid fibrils (see related news story). Writing in last week's early ...

The process of alternating elongation and pausing of amyloid β (Aβ) fibrils was captured by combining high-speed atomic force microscopy (HS-AFM) and Monte Carlo simulations. The study revealed the ...

Study may be a step toward shelf-stable versions of the hormone, which is used to control diabetes. Patients with type 1 diabetes have to regularly inject themselves with insulin, a hormone that helps ...

Research into preventing and reversing the creation of misfolded protein aggregates known as fibrils could provide new therapeutic opportunities in the fight against neurodegenerative diseases such as ...

Researchers have developed a potential new peptide-based drug delivery system by repurposing fibrils that contribute to Alzheimer’s disease pathogenesis. Researchers at the University of North ...

Growing evidence indicates that gut microbiota plays a critical role in regulating the progression of neurodegenerative diseases such as Parkinson's disease (PD) and Alzheimer's disease (AD), but the ...