A paper titled "Functional implications of unusual NOS and SONOS covalent linkages found in proteins," by Matthew D. Lloyd, Kyle S. Gregory, and K. Ravi Acharya, from the University of Bath Department ...

L1, termed IB101, which was found to form a defined binding pocket that precisely positions the active moiety in a reactive conformation.

Researchers have found a new type of cross-link between amino acids in a protein (Nature 2021, DOI: 10.1038/s41586-021-03513-3). The intramolecular linkage is an N-O-S bridge formed by oxidizing the ...

A research group has successfully demonstrated that carbon-carbon (C-C) covalent bonds expand and contract flexibly in response to light and heat. This unexpected flexibility of C-C bonds could confer ...

Graphene oxide is composed of oxygenated functional groups, the most prevalent of which are carboxyl, carbonyl, epoxy, and hydroxyl. These functional groups present on graphe are polar, making it very ...

Based on this concept, the team developed a high-throughput platform that combines yeast surface display with chemoselective protein modification to screen diverse crosslinkers and millions of protein ...

A team led by principal investigators Bobo Dang and Ting Zhou at Westlake University/Westlake Laboratory have developed a ...