Endothelial cell junctions form a dynamic interface that governs vascular permeability, tissue perfusion and homeostasis. The principal adhesive structures—adherens junctions and tight junctions—are ...
The vascular endothelium forms a dynamic barrier that regulates fluid, solute and leukocyte passage while withstanding shear stress. Integrity is governed by two principal junctional complexes: ...
Fatty streaks, one of the earliest signs of atherosclerosis, comprise lipid-laden foam cells, which are traditionally thought ...
Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...
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