Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and approximately 30% of patients develop treatment-resistant depression (TRD), a condition that does not respond ...

UB neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression ...

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed ketamine to treat ...

Activation of the body’s opioid system may be required for ketamine’s antidepressant effects, new research hinted. In a small study of adults with major depressive disorder, taking the opioid blocker ...

It's a topic that has long captivated doctors, scientists and the public — what exactly happens in your brain when you're oblivious on the operating table? Some anesthesia drugs work in a ...

For individuals facing conditions like depression, anxiety, OCD, or chronic pain, the journey to effective treatment can be long and frustrating. Traditional medications, such as SSRIs, may not always ...

Doctors say ketamine therapy can provide life-saving support in cases where other medications have failed, but there are ...

The majority of people with ketamine use disorder (KUD) don’t seek addiction treatment, despite reporting physical symptoms that include bladder and nasal problems and painful organ cramping, a large ...

Researchers from Japan have uncovered direct evidence showing how ketamine exerts its rapid antidepressant effects in ...