New treatments for depression are needed that act rapidly and also have sustained effects. Ketamine accomplishes this, but toxic side effects limit its long-term use. Scientists haven't understood how ...

In a study published in Nature Neuroscience on Sept. 14, researchers led by Dr. Chen Yelin from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences showed that the ...

Ketamine has transformed the treatment landscape for depression through its rapid amelioration of symptoms, particularly in treatment-resistant cases. Beyond its well characterised antagonism of ...

Ketamine has emerged as a paradigm-shifting intervention for individuals with depression unresponsive to standard treatments. At subanesthetic doses, its primary action is the non-competitive ...

UB neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression ...

Positron emission tomography (PET) images using the novel tracer [¹¹C]K-2 visualize cell-surface α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) density in the living human brain ...

For individuals facing conditions like depression, anxiety, OCD, or chronic pain, the journey to effective treatment can be long and frustrating. Traditional medications, such as SSRIs, may not always ...

A new study by Canadian researchers brings us one step closer to understanding the antidepressant effects of ketamine in sub-anesthetic doses. In mice, the researchers identified how two ...

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed ketamine to treat ...

For patients with treatment-resistant depression (TRD), ketamine and esketamine have offered something that conventional antidepressants often cannot: relief that can arrive quickly. But that speed ...

A single, low-dose intravenous infusion of ketamine reduced symptoms of chronic fatigue in patients suffering from various ...