In a paper published in Cell, a USC Stem Cell-led team reports a new way of generating a renewable and expandable supply of ...

Atherosclerosis is driven by a complex interplay between circulating monocytes and the vascular endothelium. Endothelial cells lining the arterial wall respond to risk factors such as hyperlipidaemia, ...

Scientists at the Immunology Frontier Research Center (IFReC) at Osaka University, Japan, report a new group of monocytes they call SatM. Studies in mice show that SatM may be responsible for causing ...

In recent decades, immunotherapy has transformed cancer treatment, offering effective options for diseases once considered uncurable, such as melanoma, lung, and bladder cancers. What began as ...

The cyclic GMP–AMP synthase–stimulator of interferon genes (cGAS–STING) pathway senses double-stranded DNA in the cytoplasm, triggering the secretion of type I and III interferons and proinflammatory ...

Combining a serum-free medium with a xeno-free serum replacement creates a reliable system for generating functional dendritic cells and macrophages. Myeloid cells such as dendritic cells and ...

Blocking a signaling pathway in certain white blood cells may prevent clots from obstructing blood flow and causing CTEPH, per a new study.

MLR may be a useful marker for assessing activity and progression in chronic lymphocytic leukemia (CLL). Patients with CLL had significantly lower MLR values compared to healthy individuals, with ...

Diffuse Alveolar Damage (DAD), a severe pathological consequence of acute lung injury triggered by factors like infection or toxins, features intense inflammatory cell infiltration and carries a high ...

Rheumatoid arthritis (RA) is an autoimmune disease that causes joint inflammation and destruction. 1 There is currently no cure – and although there are many treatments, their effectiveness varies ...

Hematopoietic cell transplantation (HCT), also known as bone marrow transplantation, is a critical treatment for blood cancers such as leukemia, lymphoma, and myeloma, as well as certain genetic and ...