Mycobacterium tuberculosis infects the respiratory tract and establishes a complex interplay with the host immune system. Upon inhalation, bacilli are phagocytosed by alveolar macrophages but evade ...

The advent of high‐throughput sequencing and advanced analytical frameworks has transformed our understanding of Mycobacterium tuberculosis pathogenicity. Genomic comparisons across clinical isolates ...

Tuberculosis (TB) is an infectious disease that kills more than a million people worldwide every year. The pathogen that causes the disease, Mycobacterium tuberculosis, is deadly in part because of ...

Mammalian hosts coordinate various cell death pathways as part of the immune defense system against pathogens including Mycobacterium tuberculosis (Mtb), which causes tuberculosis featuring lung ...

A researcher team from Ecole Polytechnique Federal de Lausanne led by Dr. Vivek Thacker now group leader at the Department of Infectious Diseases at Heidelberg University Hospital have studied why ...

Tuberculosis (TB) is an infectious disease that kills more than a million people worldwide every year. The pathogen that causes the disease, Mycobacterium tuberculosis, is deadly in part because of ...

Verma and colleagues interrogate the mechanisms of phagosome maturation arrest during Mycobacterium tuberculosis infection. While cellular events that culminate in this arrest have been largely ...

Scientists discovered genes in the tuberculosis bacterium that becomes essential for the pathogen's survival when it's exposed to air through coughing. These genes could be targets for new therapies ...

How did you get interested in science? I always did well in science, but I did not develop a true interest in the subject until my research experience after completing my bachelor’s degree in ...

Figure 3. Pre-activation of alveolar-like macrophages with IFN-γ and MTb cues reduces their capacity to restrict C. neoformans growth. Cryptococcus neoformans is one of four fungi classified as ...

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), remains a leading infectious threat to public health worldwide. It is estimated to have infected 2–3 billion people and ...

New technologies like wastewater surveillance have enabled public health officials to monitor the spread of a few infectious diseases in a community by identifying known pathogens by their DNA. While ...