The human brain constantly adapts in response to experiences, forming new connections between neurons and reorganizing ...

Researchers use cryo-EM to reveal how the NMDA receptor's Asn cage filters calcium from magnesium to drive learning and ...

Drugs that act on NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, are key for treating neuropsychiatric disorders. These drugs were ...

One of several types of ligand-gated ion channel, the N-methyl-D-aspartate (NMDA) receptor transmits excitatory stimuli in the brain. When calcium flows through this channel, neural plasticity happens ...

Researchers have obtained images of the NMDA receptor in active, non-active, and inhibited states. Understanding how NMDA receptors activate is critical in designing novel therapeutic compounds for ...

Excitatory amino acid receptors of the N-methyl-D-aspartate (NMDA) subtype are ligand-gated cation-selective ion channels. The unusual properties of NMDA receptors, and particularly of their channel, ...

The modulation of neuronal glutamate receptors by phosphorylation is considered to be critical for synaptic plasticity. In particular, altering NMDA–type glutamate receptor properties by ...

The difference between mental health and mental illness can turn on changes in brain cells and their connections that are almost incomprehensibly tiny, at least in physical terms. This irony is ...

Depressed teenager The designation is supported by data from a phase 2 study, which showed that REL-1017 produced rapid, robust, and sustained antidepressant effects vs placebo. The Food and Drug ...

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural ...

Picture every synapse in your brain as a phone line. About 70% of them are live, carrying signals right now. But according to ...

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural ...