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The norovirus genome encodes seven nonstructural and two structural proteins (). 5,13 The majority of reverse-transcriptase–polymerase-chain-reaction (RT-PCR) diagnostic assays target the RNA ...
Finally, the norovirus genome easily undergoes mutation that causes antigenic shift and recombination, which, in turn, result in the evolution of new strains that are able to infect susceptible hosts.
Norovirus. Image Credit: Kateryna Kon/Shutterstock.com. ... Noroviruses have a linear, 7.5kb, single-stranded RNA genome with a positive polarity which encodes three open reading frames (ORFs).
We propose that these condensates are replication hubs for human norovirus, an elegant solution to the puzzling question of how ribosome-assisted translation of the viral genome is segregated from its ...
The surrogate virus, murine norovirus-1, can be grown in cell culture, and belongs to the same genus as human norovirus, and has a very similar genome structure, and morphology.
The scientists inserted a key norovirus gene into the genome of a harmless rotavirus, so that the latter would form proteins that make up the outer surface of norovirus.
Every year, norovirus causes hundreds of millions of cases of food poisoning -- and the deaths of at least 50,000 children -- yet there exists no real way to control it.