Nucleic acids are chains of nucleotides that are a vital part of all living beings. The two most common types of nucleic acids are deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), which provide ...

What are spherical nucleic acids (SNAs)? What do they consist of and how do they differ from linear nucleic acids? Spherical nucleic acids are structures that are made by taking a nanoparticle ...

Nucleic acid extraction is a fundamental step in unlocking the genetic information contained within biological samples. Isolated nucleic acids are the basis for a multitude of analyses and ...

The intracellular environment is highly compartmentalized; biomolecules (nucleic acids, proteins, lipids and so on) are spatiotemporally organized to form functional modules, signal pathways and ...

The development of nucleic-acid therapeutics, ranging from aptamers and antisense RNA to messenger RNA (mRNA)-based vaccines and gene therapies, is a rapidly evolving industry that has the potential ...

Gastrointestinal (GI) cancers remain a major global health burden, accounting for substantial cancer-related morbidity and mortality worldwide. Cell-free ...

Our research focuses on all aspects of nucleic acid structure, chemistry and function employing state of the art technologies and approaches. The structure and chemistry of nucleic acids is ...

Biocompatible silicon nanoneedles, which can efficiently deliver nucleic acids and nanoparticles into biological cells without damaging them, have been developed by an international team of ...

Some biologists have long hoped that small pieces of RNA that silence genes could help wipe out genetic diseases. But developing nucleic acid medications with good drug properties, such as selectivity ...

The research focus of the Müller group is the bioinorganic chemistry of nucleic acids with a particular emphasis on the generation, characterization as well as application of nucleic acids including ...

Nucleic acids such as DNA and RNA play a central role in gene therapies and vaccines. They store and transmit biological information. In order for them to work in the body, they must enter the cells ...