The recommendations follow the World Health Organization’s recent update to its classifications of central nervous system (CNS) tumors to now include a structure for pediatric patients with CNS tumors ...

Sequencing circulating tumor cell-free DNA (cfDNA) in cerebrospinal fluid (CSF) improved diagnosis, decision-making, and clinical care in pediatric and adolescent and young adult (AYA) patients with ...

Lumps and bumps are common in childhood, but when they form in soft tissue without an obvious cause, they could be pediatric soft tissue sarcoma (STS). In children, cancer that forms in the soft ...

Pediatric non-small cell lung cancer (NSCLC) is a type of lung cancer that affects children and adolescents. It may be treatable using methods such as surgery and chemotherapy. Pediatric NSCLC is the ...

Please provide your email address to receive an email when new articles are posted on . The FDA granted accelerated approval to entrectinib for infants aged 1 month and older who have solid tumors ...

In an early-stage clinical trial, the therapy nearly doubled the expected survival time of young patients. Still, experts caution that more research is needed. Gavin Nielsen was 2 years old when he ...

Cancer therapies targeting specific genetic mutations may offer benefits to patients for whom other standard chemotherapy treatments have not effectively treated their tumor. However, genetic ...

We conducted a prospective precision medicine trial, using whole-exome sequencing of tumor and germline tissue and whole-transcriptome sequencing (RNA Seq) of tumor tissue to characterize the ...

PHILADELPHIA, Nov. 21, 2025 /PRNewswire/ -- Researchers at Children's Hospital of Philadelphia (CHOP) and Children's National Hospital in Washington D.C. are uncovering how rare inherited genetic ...