Nature

Questions arising on phlebotomy in polycythemia vera: prophylactic measures to reduce thromboembolic events require patient-focused decisions

Phlebotomy is a cytoreductive measure to gradually reduce cellularity and therefore hematocrit of PV patients. In their treatment recommendations published in this journal, Barbui et al. [6] provide a ...
Nature

A prospective cohort study of the feasibility and efficacy of iron reduction by phlebotomy in recipients of hematopoietic SCT

There are several unanswered questions in this area. First, it is not clear how to best measure iron overload in these patients. Second, the exact mechanism whereby iron overload causes increased ...