BK polyomavirus is a major source of kidney damage and rejection in transplant recipients. But a novel way has been found to decrease BK polyomavirus levels in transplant patients without decreasing ...

A benign virus normally found in the skin can lead to a type of rare, lethal skin cancer. Specifically, infection by the Merkel cell polyomavirus can lead to Merkel cell carcinoma in ...

While uncommon, BK polyomavirus-associated nephropathy is associated with a "substantial" risk of graft loss in kidney transplant recipients. BK polyomavirus-associated nephropathy may increase the ...

It has recently been shown that Merkel cell carcinoma, a rare and often lethal cutaneous malignancy, frequently harbors a novel clonally integrated polyomavirus aptly named Merkel cell polyomavirus.

If every cell in our body is a factory, viruses are industrial spies who try to break in and take over. New findings about how one of the most mysterious types of spy - polyomaviruses -- accomplishes ...

Background A 36-year-old white female, who had received a deceased-donor kidney transplant for end-stage renal disease secondary to reflux nephropathy 8 years previously, was referred to a transplant ...

From July 2001 to April 2004, we used leflunomide as the initial antiviral therapy in 17 patients with biopsy-proven BK nephropathy. All but one of these patients was receiving tacrolimus, prednisone, ...

Background. A 33 year-old pancreatic transplant recipient developed weakness, retinal blindness, and necrotic plaques on her face, scalp, and hands. Methods. A muscle biopsy was analyzed by light and ...

When and what diagnostic procedures should be done on follow-up of a patient who lost renal function after a verified polyomavirus infection in a renal graft? Is the virus latent after infection, or ...

Introduction: The risk of polyomavirus-associated nephropathy (PyVAN) currently ranges from 1% to 10%, and the risk of graft loss is 10% to 50% within 2 years post-diagnosis. There is currently no ...

ANN ARBOR, Mich. -- Every cell in our body runs like a tiny factory that makes specialized products, using the carefully guarded instructions kept in the CEO's office. But every once in a while, an ...