Depurination of DNA and RNA sequences is an alteration of the sugar-phosphate backbone in which hydrolysis of a purine base (adenine or guanine) occurs. Synthetic oligonucleotides suffer from such ...

Researchers from Japan enhanced the hydrogen evolution reaction (HER) by modifying platinum cathodes with purine bases. The purine molecules form hydrogen-bonded cages with surrounding water, which ...

Acyclic nucleoside phosphonates (ANPs) represent a vital class of compounds with significant applications in antiviral and antiparasitic therapy. Characterised by a non-hydrolyzable phosphonate group, ...

This image illustrates the chemical structures of the five main nucleobases found in DNA and RNA. The pyrimidines, thymine (DNA), uracil (RNA), and cytosine are shown on top while the purines, adenine ...