For decades, oncologists have watched a frustrating pattern repeat itself. Tumors fueled by the MYC protein, one of the most ...
Chemotherapy drugs like doxorubicin and etoposide work by snapping a cancer cell’s DNA in two. The breaks are supposed to be ...
Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
Researchers at The University of Texas Medical Branch (UTMB) have identified how a key enzyme called ATR protects DNA from ...
When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...
DNA replication is a tightly controlled process that copies the genetic code, allowing its instructions to be conveyed from one generation of cells to the next. In diseases like cancer, these ...