Proteins are the infinitely varied chemicals that make cells work, and science has a pretty good idea how they are made. But ...

Scientists at UCL have discovered a novel role played by ribosomes during the folding of new proteins in cells, described in ...

Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, ...

The researchers wanted to find a way to watch this ribosome-assembly process play out. Everything begins with RNA produced in the nucleolus’s innermost layer. That RNA assembles into components of ...

The ribosome moves along the mRNA, reading the codons one by one. For each codon, the corresponding tRNA molecule carrying the appropriate amino acid binds to the ribosome. The peptidyl transferase ...

A new method for studying ribosome function UIC scientists use native chemical ligation to fuse peptides to tRNAs Date: November 1, 2022 Source: University of Illinois Chicago ...

This new review article highlights the critical role of ribosome biogenesis in liver health and disease progression.

When ribosomes go rogue Unusual variations in the cellular protein factory can skew development, help cancer spread, and more. But ribosome variety may also play biological roles, scientists say.

“We wanted to know how quickly a human ribosome can read the genetic code, how quickly it finds the tRNA that’s complementary to the mRNA,” explained said co-first author Mikael Holm, PhD.

Led by Northwestern Engineering’s Michael Jewett, researchers created a new version of an engineered tethered ribosome dubbed Ribo-T, which provides a foundation to propel broad, new efforts in ...