Gene editing can repair mutations that prematurely halt protein synthesis, resulting in incomplete peptides that cause ...

An archaeon reads the same codon in two different ways, overturning a doctrine that has stood for 60 years. Living organisms ...

UC Berkeley scientists discovered that a microbe can interpret the UAG stop codon in two ways, producing different proteins ...

When Daniel Fischer cofounded Tevard Biosciences in 2017, he wasn’t trying to bet on the next hot RNA technology. His interest was more personal. His daughter Natasha has Dravet syndrome, a rare form ...

A messenger RNA (mRNA) does more than provide ribosomes a template for creating a sequence of amino acids. It also conveys regulatory information, including so-called stop codons. But just as cars ...

The genetic code is the recipe for life, and provides the instructions for how to make proteins, generally using just 20 ...

Accurate protein synthesis is a tightly controlled biological process with multiple quality control steps safeguarded by aminoacyl-transfer RNA (tRNA) synthetases and the ribosome. Reduced ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 26 (Jun. 26, 2007), pp. 10824-10829 (6 pages) In universal-code eukaryotes, a single-translation ...

Translation termination takes place when one of three stop codons is recognized by a proteinaceous class 1 release factor (RF) in the A site of the ribosome. The RFs are bifunctional molecules, like ...

A molecular biologist from Lomonosov Moscow State University together with foreign colleagues discovered a special mechanism of protein synthesis regulation that they called a "molecular timer". It ...

It has long been assumed that there is only one 'canonical' genetic code, so each word means the same thing to every organism. Now, this paradigm has been challenged by the discovery of large numbers ...