In a recent study published in the journal Nature Communications, researchers present a method for constructing artificial viral vectors (AVVs) using the established structural components of ...
Venigalla B. Rao, PhD, has been studying bacteriophages for more than four decades, mostly in small laboratories with limited personnel and funding. But having a mere eight-person lab (four post-docs, ...
The study may provide clues to how similar viruses infect cells and suggest ways for developing a new class of antibiotics and other drugs to prevent illnesses caused by viral pathogens. Scientists at ...
This is a preview. Log in through your library . Abstract The synthesis of deoxynucleotide kinase (EC 2.7.4.2) in vitro by a preparation consisting of T4 bacteriophage DNA and a cell-free extract of ...
A team of scientists from the United States has recently developed a bioengineered bacteriophage T4 nanoparticle structure using CRISPR technology that can be used as a universal platform to produce ...
WEST LAFAYETTE, Ind. – New findings in research led by Purdue University biologists provide further evidence that the protein envelope protecting DNA in viruses evolved billions of years ago from a ...
Replication of DNA requires helicase and primase activities as part of a primosome assembly. In bacteriophage T4, helicase and primase are separate polypeptides for which little structural information ...
(Nanowerk News) International researchers have built artificial virus-like particles capable of entering human cells to perform tasks such as gene editing. In a proof of concept study, the team used a ...
Current calibration methods rely on artificially constructed DNA structures or specific cellular features, each with significant drawbacks. DNA-based rulers require complex chemical synthesis and only ...
The following two articles are concerned with the genetic control of mutation rate. The first describes the anti-mutagenic effect of some DNA polymerase mutations on phage T4 mutation rates, and ...
WEST LAFAYETTE, Ind. — A detailed look at a syringe-like structure designed to inject viral DNA into a host cell reveals a unique and complex entry scheme for viruses. The study may provide clues to ...
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