In Week 5, nine underdogs covered in 14 games and every one of our NFL experts finished with a record above .500.

It's another intriguing slate of NFL contests in Week 6 as we approach the middle of the season. Here are the picks against the spread from our expert staff. Opening Line: Eagles -7 Grimes: Eagles -7.5 A perfect get-right game for the Eagles, unfortunately.

For a second time in our 2025 expert picks, the Carolina Panthers rewarded the faith of their lone believer. This time—in Week 6 —it was John Pluym, managing editor of Sports Illustrated 's MMQB. Pluym was just one of the 44 experts we documented who picked the Panthers to best the Dallas Cowboys last week.

And then there were none. Entering Week 5, there were just two undefeated teams remaining in the NFL, but both fell at home.

You can also see the model's best bets for every Week 6 NFL game, including Cowboys vs. Panthers, Seahawks vs. Jaguars and Chiefs vs. Lions. Finally, SportsLine expert RJ White, who is 57-35 (+2470) over his last 92 NFL picks, has locked in multiple Week 6 ...

The San Francisco 49ers will take on the Tampa Bay Buccaneers this week. Here's what the experts think will happen on Sunday at Raymond James Stadium

"NFL Fantasy Live" anchor Patrick Claybon, fantasy analyst Adam Rank, and analytics expert Cynthia Frelund discusses which players to target on the waiver wire after Week 9 of the 2025 NFL season.

NFL experts from around the league make their picks from the Tennessee Titans and Los Angeles Chargers Week 9 matchup.

“Denver beat Dallas for the seventh straight time Sunday. The last Cowboys team to beat the Broncos was coached by Barry Switzer and got 114 rushing yards from Emmitt Smith. Bo Nix threw four touchdown passes and J.K. Dobbins rushed for 111 to keep the streak alive,” Josh Kendall and Chad Graff write. See the full rankings.

The NFL season continues in Week 9 when the New England Patriots host the Atlanta Falcons on Sunday. Start time, how to watch, streaming and NFL TV schedule.