The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

What instructions prevent premature mRNA translation before fertilization? In the 1960s and 1970s, scientists asked this question and came up with two possible answers. In 1966, Alexander Spirin ...

During the oocyte-to-embryo transition (OET), the length of the mRNA poly(A) tail is closely linked to its translational efficiency. Regulation of the poly(A) tail is essential for selective protein ...

However, the therapeutic effectiveness is limited by the poor translation uptake of naked mRNA. To circumvent this challenge, researchers from VIB, VUB, Ghent University, and eTheRNA ...

(Image: ttsz/iStock via Getty Images Plus) The Role of mRNA in Gene Expression Messenger RNA is an essential component of the gene expression process, which involves the conversion of genetic ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

In the course of these studies, we found that 3′UTRs determine where in the cytoplasm an mRNA transcript is translated. Moreover, we found that the cytoplasm is highly compartmentalized into different ...

Translation is the biological process where genetic information is used to build proteins. The following is a simplified account of how this occurs. DNA is transcribed into messenger RNA (mRNA).

Regulation of the poly(A) tail is essential for selective protein translation in early embryos. However, the mechanisms that determine and maintain the length of maternal mRNA poly(A) tails remain ...