Guidelines recommend a trial of antiarrhythmic drugs before catheter ablation for persistent atrial fibrillation. Whether pulsed field ablation (PFA) may be a preferred initial treatment is ...

Blood-pressure reduction is the only proven treatment to prevent stroke. Whether a single pill that combines three ...

Whether treatment with balanced crystalloid fluid leads to better outcomes than 0.9% saline in children treated for septic ...

There has been substantial interest in the development of GLP-1 drugs and optimism about their public health effects. But some worrisome signals related to disordered eating have emerged.

Drug-overdose deaths among adolescents have increased in recent years. Steps can be taken to equip adolescents with the knowledge and tools they need to keep themselves safe.

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 3).

The Pediatric Research Equity Act was intended to promote the development and testing of prescription drugs for children. But ...

The resident presented a patient admitted for chest pain after walking his dog. The attending asked, “What was the name of his dog?” The resident was stumped. Four years later, he’s not sure anythi ...

Explore this issue of The New England Journal of Medicine (Vol. 390 No. 10).

Explore this issue of The New England Journal of Medicine (Vol. 394 No. 8).

More than 470,000 patients with kidney failure receive hemodialysis in the United States alone, with worldwide estimates approaching 3 million patients. Mortality from kidney failure remains ...

Despite the implementation of efficacious interventions for secondary prevention, patients with ischemic stroke or transient ischemic attack (TIA) remain at substantial residual risk for short- and ...