Trichodysplasia spinulosa–associated polyomavirus was identified as a likely cause of neuroinvasive infection in a ...

A 65-year-old man was admitted to this hospital because of fever, intermittent abdominal pain, and rash. The fever began 5 weeks earlier, and palpable purpura developed 1 week before admission. A ...

A 3-year-old boy with chemotherapy-resistant metastatic hepatoblastoma had complete regression lasting at least 12 months after two infusions of glypican-3–specific CAR T cells coexpressing ...

Many patients with chronic obstructive pulmonary disease (COPD) have exacerbations despite receiving standard-of-care inhaled ...

For more than 25 years, narcolepsy type 1 (formerly narcolepsy with cataplexy) has been known to be associated with a deficiency of orexin within cerebrospinal fluid (CSF) and reduced staining of ...

Patients are at increased risk for recurrent ischemic events after an acute coronary syndrome event. Milvexian, an oral ...

Nonobstructive hypertrophic cardiomyopathy (HCM) is a common condition that is associated with substantial morbidity and no ...

Approximately one half of patients undergoing transcatheter aortic-valve implantation (TAVI) have concomitant coronary artery ...

Whether catheter-directed thrombolysis improves clinical outcomes in patients with intermediate-high–risk pulmonary embolism, ...

Pulmonary hypertension that is caused by left heart disease and is associated with heart failure may be driven by sympathetic ...

The effectiveness and safety of statins for the primary prevention of cardiovascular events and the extension of disability-free survival among older adults remain uncertain. We conducted a ...

Atherosclerosis may begin in early adulthood and remain clinically silent for decades before cardiovascular disease manifests. Although silent atherosclerosis is associated with cardiovascular ...