Here, we review data concerning the configuration of the IG genes in CLL and how studies of these genes have shed light on the pathogenesis and progression of CLL. In normal B cells, replacement ...

Immunoglobulins (antibodies) are Y-shaped proteins made by plasma cells that help fight infection. They neutralize invaders, tag them for macrophages, and trigger other immune responses. Each antibody ...

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1 Department of Sport and Physical Rehabilitation Sciences, Tshwane University of Technology, Pretoria, South Africa 2 Department of Immunology, University of the Witwatersrand, Witwatersand, South ...