Minecraft is one of the most enduringly popular games on Earth, with over 212 million active monthly players. The beloved video game even has a recent film adaptation. This popularity stems largely ...

Genetic variation influences biological processes across scales; however, deciphering how effects propagate from molecules to whole organisms remains a key challenge in human genetics. In this Review, ...

This study shows that virtually every pancreatic adenocarcinoma, regardless of specific genetic alterations, comprises six molecularly distinct cell states whose spontaneous and drug-mediated ...