A study led by the University of Barcelona and the Spanish National Research Council's Institute for Advanced Chemistry of Catalonia (IQAC - CSIC) presents a new therapeutic tool capable of inhibiting ...

UCSF researchers designed new drug candidates that potently block MPro, a viral enzyme that's crucial for SARS-CoV-2 replication. One of these drug candidates, AVI-4516, is shown (center) bound to the ...

Microscope image of human epithelium cells (blue) infected with SARS-CoV-2 (red), showing the virus spreading from one cell to another. LA JOLLA, CA—Despite vaccines and treatments, SARS-CoV-2—the ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a ...

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A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced ...

Researchers from the Institute for Basic Science of Korea and collaborating institutions have designed a new class of peptide-based inhibitors targeting a crucial interface within the SARS-CoV-2 ...

Findings reveal coronaviruses exploit stress-linked tRNA modifications, enhancing translation efficiency and offering insights for antiviral drug development.

Forget about locating molecules in the blink of an eye, which takes as long as a quarter second—far too long a time to distinguish a sequence of subcellular events. Instead, try doing what Stanford ...

Many proteins have a complex architecture that enables biological functions. Molecules can bind to specific sites on a protein and alter its function. A team at HZB has now investigated the Nsp1 ...