DOPE-Cx can form a special structure called a "cubic phase," which helps overcome a major challenge in mRNA delivery by LNPs: endosomal escape. LNPs are taken into the cell in the form of endosomes, ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered that m6A methylation regulates the production of proteins essential for ...

Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

Researchers have successfully 3D printed insulin-producing human pancreas cells that could revolutionize treatment for Type 1 ...

Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

Cancer cells can acquire energy-generating structures called mitochondria from nearby nerve cells, which seems to aid their ...

The agreement also endorses the “One Health” approach, which integrates human, animal, and environmental health.

One type of RNP, hnRNPs (heteronuclear proteins), are important in splicing of mRNA (messenger RNA), polyadenylation, stabilization, localization and translation. Latest Research and Reviews ...

While US exceptionalism may have lost some of its shine, it is worth remembering that the US stock market remains home to ...

A new gene therapy delivery device could let hospital pharmacies make personalized nanomedicines to order. This democratized ...

The printed cells remained alive and functional in test tubes for up to three weeks, maintaining strong insulin responses to glucose and showing real potential for future clinical use, the researchers ...