DOPE-Cx can form a special structure called a "cubic phase," which helps overcome a major challenge in mRNA delivery by LNPs: endosomal escape. LNPs are taken into the cell in the form of endosomes, ...

Summary: New research reveals how a tiny chemical mark on RNA helps wire the brain during development. Scientists discovered that m6A methylation regulates the production of proteins essential for ...

The structure will facilitate the interpretation in molecular terms of lower resolution ... The 30S ribosomal subunit has a crucial role in decoding mRNA by monitoring base pairing between ...

Using capillary gel electrophoresis, researchers from the National Institute of Health Sciences in Kanagawa, Japan studied the factors that optimize chain-length distribution analysis of messenger RNA ...

Scientists have discovered the internal shape of tiny drug-delivery particles – called lipid nanoparticles – has a big impact ...

Based on several lines of interesting data, the authors conclude that FMRP, though associated with stalled ribosomes, does not determine the position on the mRNAs at which ribosomes stall. Although ...

Researchers have successfully 3D printed insulin-producing human pancreas cells that could revolutionize treatment for Type 1 ...

Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...

Smart mRNA drugs that listen to the body: A new era in precision medicine. Jun 19, 2025. Scientists discover new approach to gene therapy. Jun 19, 2025. High-speed AFM and 3D modelling help towards ...

Key TakeawaysThe global vaccines market reached USD 87.57 billion in 2024 and is projected to grow to USD 206.78 billion by ...

An enzyme type noted in several cancers is the family of adenosine deaminases acting on RNA (ADARs). These enzymes convert ...