gut.bmj1d
Alternative treatments for type 2 diabetes and associated metabolic diseases: medical therapy or endoscopic duodenal mucosal remodelling?
Correspondence to Professor Jacques J G H M Bergman, Gastroenterology and Hepatology, Amsterdam UMC Location AMC, Amsterdam 1105 AZ, The Netherlands; j.j.bergman{at}amsterdamumc.nl Despite important ...
gut.bmj3d
Tumour-educated circulating monocytes are powerful candidate biomarkers for diagnosis and disease follow-up of colorectal cancer
Objective Cancer immunology is a growing field of research whose aim is to develop innovative therapies and diagnostic tests. Starting from the hypothesis that immune cells promptly respond to harmful ...
gut.bmj3d
Faecal metabolome and its determinants in inflammatory bowel disease
Objective Inflammatory bowel disease (IBD) is a multifactorial immune-mediated inflammatory disease of the intestine, comprising Crohn’s disease and ulcerative colitis. By characterising metabolites ...
gut.bmj3d
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis
Objective Hepatic stellate cells (HSC) transdifferentiation into myofibroblasts is central to fibrogenesis. Epigenetic mechanisms, including histone and DNA methylation, play a key role in this ...
gut.bmj4d
Role of mast cells in chronic stress induced colonic epithelial barrier dysfunction in the rat
Intestinal Disease Research Program, Department of Pathology and Molecular Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, L8N 3Z5, Canada M H Perdue, Intestinal Disease ...
gut.bmj4d
Colorectal cancer screening uptake over three biennial invitation rounds in the English bowel cancer screening programme
Objective To examine patterns of colorectal cancer (CRC) screening uptake over three biennial invitation rounds in the National Health Service (NHS) Bowel Cancer Screening Programme (BCSP) in England.
gut.bmj5d
Microbiota-induced S100A11-RAGE axis underlies immune evasion in right-sided colon adenomas and is a therapeutic target to boost anti-PD1 efficacy
2 Key Laboratory of Human Microbiome and Chronic Diseases (Sun Yat-sen University), Ministry of Education, Guangzhou, China Background Tumourigenesis in right-sided and left-sided colons demonstrated ...
gut.bmj7d
Visceral hypersensitivity in non-erosive reflux disease
1 Neurogastroenterology Group, Centres for Academic Surgery, Institute of Cellular and Molecular Science, Barts and the London, Queen Mary’s School of Medicine and Dentistry, Whitechapel, London, UK 2 ...
gut.bmj7d
Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets
1 Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, the Netherlands 2 Department of Experimental Internal Medicine, Academic Medical Centre, Amsterdam, the Netherlands ...
gut.bmj8d
Impairment of intestinal glutathione synthesis in patients with inflammatory bowel disease
a Department of Surgery, University of Heidelberg, Heidelberg, Germany, b Department of Immunochemistry, German Cancer Research Center, Heidelberg, Germany Dr B Sido, Department of Surgery, University ...
gut.bmj9d
Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways
2 Microbiology and Tumour Biology Centre, Karolinska Institute, Stockholm, Sweden 3 Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden 4 Microbiology and Tumour ...
gut.bmj10d
Efficacy and safety of endoscopic resection of large colorectal polyps: a systematic review and meta-analysis
Objective To assess the efficacy and safety of endoscopic resection of large colorectal polyps. Design Relevant publications were identified in MEDLINE/EMBASE/Cochrane Central Register for the period ...