Iran's supreme leader warned the U.S. would face "irreparable damage" if it joined Israel's conflict with Iran. Who is ...

Ayatollah Ali Khamenei rejected President Trump's demand for unconditional surrender, as Iranians jammed the highways out of Tehran.

Calling out Trump directly, the Supreme Leader added: “The U.S. President threatens us. With his absurd rhetoric, he demands ...

In a post on his Truth Social platform, Trump had directly threatened the Iranian Supreme Leader, saying he knew "where the ...

Israel said it had struck uranium enrichment sites in Iran after the two countries launched another barrage of missiles at ...

The cleric has ruled for more than three decades, spearheading a policy of backing proxy groups to wield influence across the ...

Ayatollah Ali Khamenei has spent almost four decades as Shi'ite Iran's supreme leader building a regional power to rival the ...

Explosions were heard in Iran's capital as Israeli warplanes pounded Tehran overnight and into Wednesday. Less than a week ...

In an ABC News exclusive, Israeli PM Benjamin Netanyahu speaks with Jon Karl about the conflict with Iran -- and says he's not ruling out taking out Iran's supreme leader, Ali Khamenei.

Israel attacked Iran early Friday with a barrage of airstrikes that took out top military officers and hit nuclear and ...