The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...
Single-cell RNA sequencing (scRNA-seq) data from published datasets were obtained to investigate the expression and ...
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Table 1: Differences between prokaryotes and eukaryotes. In prokaryotic cells, transcription and translation are coupled, meaning translation begins during mRNA synthesis. 6 In eukaryotic cells, ...
The Kowalinski group at EMBL Grenoble discovered notable differences between the nuclear cap-binding complex in trypanosomes and humans, a critical component in cellular RNA metabolism. Trypanosomes ...
Trypanosomes are parasites that cause sleeping sickness, Chagas disease, and various animal diseases. Diagnosis and treatment remain complex and no effective vaccine has been developed. A better ...
The most prevalent chemical modification in eukaryotic mRNAs is m 6 A methylation. It regulates various biological processes, including mRNA stability and translation efficiency, by modulating ...