Medications targeting the neonatal fragment crystallizable receptor have gained attention due to multiple recent FDA ...

A 58-year-old woman was admitted to the hospital 3 weeks after lumbar surgery because of diplopia and fever. Left leg pain and a rash had preceded the fever and diplopia. A diagnosis was made.

Atherosclerosis is a lipid-driven chronic inflammatory disease that is modulated by innate and adaptive immunity including humoral immunity. Importantly, antibody alterations achieved by genetic means ...

As scientists uncover how age-altered antibodies ignite inflammation and tissue decline, a new era of immune-based anti-aging therapies is beginning to emerge. Aging affects B cells and induces ...

Researchers at UMC Utrecht have discovered that converting monoclonal antibodies from the IgG to the IgM isotype can significantly broaden their ability to recognize and bind multiple human-relevant ...

This paradigm-shifting finding redefines our understanding of how antibodies defend the body and could pave the way for next-generation antibody-based therapies. Many bacteria experience mechanical ...

Background: Infectious processes are the leading cause of pediatric consultation, and recurrent or severe infections may indicate primary immunodeficiencies (PIDs), which comprise more than 484 rare ...

This important study utilizes humanized mice, in which human immune cells are introduced into immune-deficient mice, to provide convincing evidence that two helper CD4 T-cell subsets, T-follicular ...