This study provides important insights into how IL-1 cytokines protect cells against SARS-CoV-2 infection. By inducing a non-canonical RhoA/ROCK signaling pathway, IL-1beta inhibits the ability of ...
Bronchial epithelia are the primary target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. Here, we reconstituted bronchial epithelia from adult and child donors and show ...
Researchers have discovered a new phenomenon where sperm from mice can induce non-reproductive cells from hamsters to fuse and form a syncytia – a cell with multiple nuclei. The study, published today ...
A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease. If Kupffer cells (KCs), a specific kind of immune cells found in the liver, become impaired by ...
JACKSONVILLE, Fla. – UF Health, Baptist Health, Ascension St. Vincent’s, Memorial Hospital and Orange Park Medical are all dealing with patients suffering from the flu, COVID, or respiratory syncytia ...
TOPSHOT - A Registered Nurse tends to a Covid-19 patient in the Intensive Care Unit at Providence St. Mary Medical Center in Apple Valley, California on January 11, 2021. - As Covid-19 tears through ...
From a Distance (part of the “Fires of War” collection) by Susan Crile. When it comes to SARS-CoV-2 infection, our very own immune system can end up contributing to the damage. Inflammation, though an ...
A growing body of epidemiological and research data has associated neurotropic viruses with accelerated brain aging and increased risk of neurodegenerative disorders. Many viruses replicate optimally ...
A team led by Maria Leptin has shown in the fruit fly Drosophila that autophagy, a mechanism of stress responses in cells, plays an important role in wound healing: When a wound heals, the process of ...
cKing's College London, British Heart Foundation Centre of Research Excellence, School of Cardiovascular Medicine & Sciences, SE5 9NU London, United Kingdom COVID-19 is a deadly pulmonary disease with ...
The SARS-CoV-2 spike protein is responsible for host receptor recognition, membrane fusion, and viral infection. Understanding the cellular and inhibiting the molecular mechanisms of spike-driven ...
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