Bacterium that may protect against long COVID identified

According to WHO, approximately 6% of the worldwide population who contract COVID-19—some 400 million people—go on to develop ...
Science Daily

DNA origami vaccines could be the next leap beyond mRNA

RNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA ...
Pulmonology Advisor

Fourth COVID-19 BA.1-Adapted Vaccine Dose Safe, Confers Robust Immune Response

A 4th dose of the bivalent or monovalent Omicron BA.1-adapted BNT162b2 vaccine elicits robust neutralizing responses in adults aged 18 to 55.
IFLScience

Brain Scans Of Recovered COVID-19 Patients Reveal Microstructural And Chemical Changes

Laura holds a Master's in Experimental Neuroscience and a Bachelor's in Biology from Imperial College London. Her areas of expertise include health, medicine, psychology, and neuroscience. Laura holds ...
PNAS

SARS-CoV-2 S assembly into virions facilitated by host ERM proteins

This study reveals a critical host–pathogen interaction driving SARS-CoV-2 spike (S) protein incorporation into virions through its binding to cytoskeletal ERM proteins, a mechanism conserved among ...
eLife

The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective

A major health challenge resulting from the COVID-19 pandemic is the manifestation of post-acute sequelae of SARS-CoV-2 (PASC). PASC (or long COVID) is a collective term used for clinical symptoms, ...
The Lancet

Targeting the SARS-CoV-2 reservoir in long COVID

bDepartment of Infectious Diseases and Unit of Post-COVID Huddinge, Karolinska University Hospital, Stockholm, Sweden cDepartment of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden ...
C&EN

Structure-Guided Temporin L Analogs Development to Inhibit the Main Protease of SARS-CoV-2

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Peptide-based inhibitors exhibit considerable potential as antiviral agents targeting ...
Kaleido Scope

SARS-CoV-2 drives lung foam cell formation linked to long-COVID damage, study finds

A multi-institutional study led by researchers at the University of Alabama at Birmingham and the University of North Carolina at Chapel Hill has revealed a previously underappreciated mechanism by ...
Live Science

'We have basically destroyed what capacity we had to respond to a pandemic,' says leading epidemiologist Michael Osterholm

Live Science spoke with leading epidemiologist Michael Osterholm about his new book, "The Big One," which discusses the next pandemic and how to mitigate its harm. When you purchase through links on ...
GEN

Host Proteins Identified in SARS-CoV-2 Replication Pathways Reveal Drug Targets

The global pandemic may be over, but SARS-CoV-2 continues to infect people around the world. Indeed, the United States has recorded roughly 750 deaths from COVID-19 over the past month. Now, an siRNA ...
PNAS

Broad neutralizing antibody response of a monomeric spike–based SARS-CoV-2 bivalent vaccine against diverse variants

This study analyzed the immunological mechanisms underlying the elicitation of broadly neutralizing antibodies (bnAbs) by a severeacute respiratory syndrome coronavirus 2 (SARS-CoV-2) bivalent vaccine ...