In a pivotal randomised controlled trial, the BNT162b2 mRNA vaccine (tozinameran, Pfizer–BioNTech) showed 95% or greater efficacy against symptomatic and severe COVID-19 disease due to SARS-CoV-2. 1 ...

An influenza vaccine candidate from Moderna showed promising results in a late-stage trial, bringing the drug maker one step ...

The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

Cellular membranes are, in general, impermeable to macromolecules (herein referred to as macrodrugs, e.g., recombinant protein, expression plasmids, or mRNA), which is a major barrier for clinical ...

Scientists have discovered the internal shape of tiny drug-delivery particles – called lipid nanoparticles – has a big impact ...

Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big ...

In early trading on Monday, shares of Palantir Technologies topped the list of the day's best performing components of the S&P 500 index, trading up 4.6%. Year to date, Palantir Technologies ...

mRNA occurs normally in our bodies. It carries instructions from our DNA out to the cells where these “blueprints” are used to make proteins. mRNA is inherently short-lived. It delivers instructions ...

Data from US safety monitoring systems for all COVID-19 vaccines authorised or approved by the FDA have been reviewed regularly by the ACIP COVID-19 Vaccines Safety Technical Work Group 20 and at ...

The promise of mRNA technology seemed boundless after the success of the coronavirus vaccines, but Robert F. Kennedy Jr. has singled it out for scrutiny, clouding its prospects.