mRNA-based drugs successfully delivered to intestine—without passing through the liver
Researchers at Tel Aviv University have achieved a breakthrough in drug delivery: they have successfully transported lipid ...
Human genetics provides clues to why DNA regulatory regions get 'loopy'
DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...
Business Wire1d
Maravai LifeSciences Acquires Assets and Intellectual Property from Molecular Assemblies
Justin Barbosa, GM and Vice President of TriLink Discovery, added “By integrating Molecular Assemblies technology into ...
Instant Scholar: Unraveling the structure of Ribosome: A journey through molecular biology by Dr Venkatraman Ramakrishnan
Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...
technologynetworks16d
The Secret to Antifungal Resistance Discovered in Fungal RNA
A distinction is made between different types of RNA with different functions. For example, tRNA (transfer RNA) is an adapter molecule that deciphers the genetic code on mRNA (messenger RNA) into a ...
idw17d
How fungi strengthen their defenses - and how we could break through them
Importance of RNA modifications for the development of resistance in fungi raises hope for more effective treatment of fungal ...
eLife23d
Recognition and Cleavage of Human tRNA Methyltransferase TRMT1 by the SARS-CoV-2 Main Protease
This manuscript provides important structural insights into the recognition and degradation of the host tRNA methyltransferase TRMT1 by SARS-CoV-2 protease nsp5 (Mpro). The data provide compelling ...
Pharmaceutical Technology25d
CRS-3123 by Crestone for Clostridioides difficile Infections (Clostridium difficile Associated Disease): Likelihood of Approval
CRS-3123 is under clinical development by Crestone and currently in Phase II for Clostridioides difficile Infections (Clostridium difficile Associated Disease). According to GlobalData, Phase II drugs ...
Time27d
Scientists Are Racing to Develop a New Bird Flu Vaccine
What about an mRNA vaccine for H5N1? There isn't one yet, but several companies—including Moderna, Pfizer and GlaxoSmithKline (in collaboration with CureVac)—are working on such a shot.