Researchers developed a technique to gain a deeper understanding of ribosome function and their cooperative behaviors.

The company’s pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat ... with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy.

An interesting study on RNA mobility in plants shows that a stem-bulge-stem-loop tRNA-derived structural motif is sufficient to mediate mRNA transport. A large number of mRNAs containing this motif ...

RTCB is required for the splicing of both tRNA and XBP1 mRNA, whereas the DDX1 enzymatic activity is specifically required for tRNA splicing in vivo.

mt-tRNA modifications are essential for their normal functions ... This result implies that there are may be other mechanisms independent of miRNA-mediated mRNA degradation. Interestingly, microRNAs ...

Gene products are often proteins, however non-protein coding genes can encode functional RNA, including ribosomal RNA (rRNA), transfer RNA (tRNA ... of cytoplasmic mRNA decay and comment on ...

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

Making the world smarter, happier, and richer.

Shares in CureVac have plummeted after a German court ruled that a patent it holds on mRNA-based COVID-19 vaccines was invalid. The validity of the patent is at the heart of patent litigation ...

After hours: January 31 at 7:59:52 p.m. EST ...

Finally, we will address safety and manufacturing aspects for CAR T cells and discuss mRNA technologies and automation concepts for ensuring the future availability of safe and efficient CAR T cell ...

The trial compared Moderna's MRNA-4157/V940 vaccine given alongside Merck & Co's cancer immunotherapy Keytruda (pembrolizumab) to Keytruda alone in patients with the skin cancer melanoma.